About The Role

Congruence is currently seeking a highly versatile and self-motivated bench Scientist (the level will be established based on the candidate’s background and relevant experience) to join our outstanding Biology team. In this role you will use a combination of cell biology, molecular pharmacology, and biochemical approaches, together with Congruence Therapeutics’ proprietary platform technology RevenirTM, to support the discovery and development of novel small molecule Correctors of misfolded proteins (G protein-coupled receptors, ion channels, transporters, and enzymes) for human genetic diseases. The successful candidate should have significant hands-on experience in contributing to the design, development, optimization, validation and execution of a wide range of assay formats using the best industry practices to support drug discovery programs.

The Ideal Candidate For This Role Will Have

• 1-3 years of drug discovery experience with bioassays in a pharmaceutical, biotech or CRO environment
• MSc Degree in cell biology, molecular pharmacology, biochemistry, or a related discipline
• Capability to demonstrate initiative and innovative thinking individually and within a dynamic and supportive team environment
• Relevant hands-on laboratory experience using in vitro cell culture systems (cell lines and/or primary cells) and plate-based assays (luminescence, fluorescence, UV-absorbance, TRF, FP, AlphaScreen, etc)
• Previous experience with protein expression/detection methods (including SDS-PAGE, Western blotting, Capillary electrophoresis) (an asset)
• Hands-on laboratory experience with molecular biology techniques (PCR, qPCR, sequencing, gene editing) (an asset)
• Previous experience with small molecules testing/screening (an asset)
• Ability to present data in Biology departmental meetings, as required
• Aptitude to maintain compliance in relation to Electronic Lab Notebook (ELN) filing
• Ability to rapidly acquire new skills, as needed

Attributes That Will Make You Successful At Congruence

• Passionate curiosity
• Drug hunter mentality driven by the desire to deliver new medicines to underserved patients
• Excitement for using and creating novel technologies and processes
• Strong team spirit and interpersonal skills, and interest in working with highly talented individuals in a fast-paced, goal-oriented environment
• Strong sense of engagement, ownership, accountability and independence

We Offer

• A meritocracy that is committed to delivering new medicines to underserved patients
• The opportunity to work innovatively at the interface of the dry lab and wet lab
• The prospect of getting in on the ground floor and making your mark
• Highly competitive base compensation
• Flexible policies
• Modern labs in a bio-innovation center environment

Congruence is committed to building an outstanding company with a meritocracy of ideas. We encourage applications from talented individuals of all backgrounds, including but not limited to race, ethnicity, religion, gender, sexual orientation, and age. Your application is strictly confidential.

Start Date And Contact Information

Start date is June 3rd 2024 at our facilities at the Ad Mare Bioinnovation Center in the Ville St-Laurent Technoparc, 7171 Frederick Banting, St-Laurent, Qc H4S 1Z9 Canada.